SP-13786 NEW
| Price | $42 | $98 | $157 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: SP-13786 | CAS No.: 1448440-52-5 |
| Purity: 99.96% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | SP-13786 |
| Description | SP-13786 is an inhibitor of fibroblast activation protein (FAP) and prolyl oligopeptidase (PREP) with IC50 values ??of 3.2 nM and 1.8 μM, respectively. |
| In vivo | METHODS: SP-13786 (UAMC-1110) (20 mg/kg, orally, twice a day) was used to treat Panc02-SIY cell tumor xenograft mice, and its effect on tumors in the mice was observed. RESULTS Tumor-infiltrating macrophages were reduced during UAMC-1110 administration, and UAMC-1110 significantly increased tumor-infiltrating CD8 T cells, including effector subsets. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : < 10 mg/mL (29.04 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (29.04 mM), Suspension. DMSO : 250 mg/mL (726.07 mM), Sonication is recommended. |
| Keywords | UAMC1110 | UAMC 1110 | SP-13786 | SP13786 | SP 13786 | FAP |
| Inhibitors Related | Benzyl cinnamate | Pirazolac | PREP inhibitor-1 | Sodium Iodoacetate | Teneligliptin hydrobromide | Soquelitinib | Anti-inflammatory agent 36 | Salidroside | MG-T-19 | Anti-inflammatory agent 35 | Isoegomaketone | Complete Freund's adjuvant |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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