SR59230A hydrochloride NEW
| Price | $38 | $82 | $118 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-10 |
Product Details
| Product Name: SR59230A hydrochloride | CAS No.: 1135278-41-9 |
| Purity: 99.89% | Supply Ability: 10g |
| Release date: 2026/06/10 |
Product Introduction
Bioactivity
| Name | SR59230A hydrochloride |
| Description | SR59230A hydrochloride (SR59230A HCl) is a blood-brain permeable, selective and highly potent β3-adrenergic receptor antagonist that inhibits ultradian brown adipose tissue thermogenesis and interrupts associated paroxysmal brain and body heating. |
| In vitro | SR59230A hydrochloride (100 nM-50 μM; 24 hours) can reduce cell viability in a dose-dependent manner in Neuro-2A, BE(2)C and SK-N-BE(2) NB cell lines. [1] |
| In vivo | MDMA (20 mg/kg) caused a slow rise in body temperature, reaching a maximum temperature increase of 1.8°C at 130 min post-injection. SR59230A hydrochloride (0.5 mg/kg) was able to slightly but significantly alleviate the slow rise in body temperature induced by MDMA. SR59230A hydrochloride (5 mg/kg) exhibited a significant and pronounced early hypothermic response to MDMA. [2] |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (13.82 mM), Sonication is recommended. 10% DMSO+90% Saline : 10 mg/mL (27.63 mM), Solution. DMSO : 250 mg/mL (690.78 mM), Sonication is recommended. H2O : 1 mg/mL (2.76 mM), Sonication is recommended. |
| Keywords | β3-adrenergic receptor | β3 receptor | β2 receptor | β1 receptor | SR-59230A hydrochloride | SR59230A Hydrochloride | AdrenergicReceptor | Adrenergic Receptor |
| Inhibitors Related | Trifluoperazine dihydrochloride | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Isoprenaline hydrochloride | D-Mannitol | Mianserin hydrochloride | Trazodone hydrochloride | Atenolol | Doxepin hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Bioactive Compounds Library Max | Adrenergic Receptor-Targeted Compound Library | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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