SRS11-92 NEW
| Price | $73 | Get Latest Price | Get Latest Price |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-08 |
Product Details
| Product Name: SRS11-92 | CAS No.: 1467047-25-1 |
| Purity: 98.67% | Supply Ability: 10g |
| Release date: 2026/06/08 |
Product Introduction
Bioactivity
| Name | SRS11-92 |
| Description | SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1 |
| In vitro | SRS11-92 inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells (EC50 = 6 nM).?SRS11-92 (2 M) inhibits iron-induced cell death in isolated mouse kidney proximal tubules, and fully protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia when used at a concentration of 100 nM. |
| In vivo | SRS11-92 increases survival of medium spiny neurons in rat corticostriatal brain slices in an in vitro model of Huntington s disease in a concentration-dependent manner.?SRS11-92 (3 M) increases production of reactive oxygen species (ROS) in L. major promastigotes in a time-dependent manner.?It is selectively toxic to L. major promastigotes (LD50 = 3.34 M) over U2OS human osteoblasts, RAW 264.7 macrophages, and intraperitoneal macrophages when used at a concentration of 80 M. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 10 mg/mL (28.37 mM), Sonication is recommended. 10% DMSO+90% Corn Oil : 1 mg/mL (2.84 mM), Sonication is recommended. |
| Keywords | SRS11-92 | SRS-11-92 | SRS1192 | SRS11 92 | Inhibitor | inhibit | HT-1080 | Friedreich | FRDA | Ferroptosis | cell death | ataxia | AA-9 | AA 9 |
| Inhibitors Related | Rosiglitazone | Hemin | Acetylcysteine | L-Glutamic acid | Sorafenib | Curcumin | Chloranil | L-Cystine | L-Glutamine | (-)-Epigallocatechin Gallate | Coenzyme Q10 | Sodium Molybdate |
| Related Compound Libraries | Apoptosis Compound Library | Ferroptosis Compound Library | Bioactive Compound Library | Bioactive Compound Library Plus | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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