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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Amines, Acids and Salts>Stauprimide
Stauprimide
  • Stauprimide

Stauprimide NEW

Price $419 $987
Package 1mg 5mg
Supply Ability: 10g
Update Time: 2026-04-20

Product Details

Product Name: Stauprimide CAS No.: 154589-96-5
Supply Ability: 10g Release date: 2026/04/20

Product Introduction

Bioactivity

NameStauprimide
DescriptionStauprimide is a non-broad spectrum inhibitor that binds to the MYC transcription factor NME2 and blocks its nuclear localization in ESCs, which causes down-regulation of MYC transcription.
In vitroStauprimide (10 μM; 6 hours) inhibits MYC transcription in most cell lines tested (EC50: 30 nM-8 μM), reducing MYC levels by 15% to over 90%. At 5 μM for 3 hours, it suppresses MYC transcription by decreasing NME2 nuclear translocation, and at 2-8 μM for 24-72 hours, it down-regulates MYC, inhibiting cell proliferation in vitro (IC50: 780 nM in RXF 393 cells). Stauprimide (4-10 μM; 6 hours) exhibits various EC50s and degrees of MYC mRNA down-regulation across different cell lines [1].
In vivoStauprimide (p.o.; 50 mg/kg; once daily; 30 days, 55 days) blocks tumor growth, decreases MYC protein levels in xenograft mouse with RXF 393 or CAKI-1 cells. It also inhibits MYC transcription in the RXF 393 tumor [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsStauprimide
Inhibitors RelatedStavudine | Aceglutamide | Hemin | Tamoxifen | Cysteamine hydrochloride | Guanidine hydrochloride | Hydroxychloroquine | Enzalutamide | Paeonol | Naringin | Alginic acid | Sildenafil citrate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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