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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>STF-31
STF-31
  • STF-31

STF-31 NEW

Price $30 $64 $98
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-09

Product Details

Product Name: STF-31 CAS No.: 724741-75-7
Purity: 99.97% Supply Ability: 10g
Release date: 2026/05/09

Product Introduction

Bioactivity

NameSTF-31
DescriptionSTF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.
In vitroSTF-31 selectively kills RCCs by specifically targeting glucose uptake through GLUT1. STF-31 significantly inhibits lactate production and extracellular acidification in VHL-deficient cells by about 60%, and decreases glycolysis by decreasing glucose transport. [1] In NAPRT1-expressing cells, STF-31 shows cytotoxicity by inhibiting the enzymatic activity of NAMPT. [2] STF-31 is toxic to hPSCs and efficient for selective elimination of hPSCs from mixed cultures. [3]
In vivoIn mice with VHL-deficient RCC xenografts, a more soluble analog of STF-31 (11.6 mg/kg, i.p.) markedly delays tumor growth. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.72 mM), Sonication is recommended.
Ethanol : 25 mg/mL (59.03 mM), Sonication is recommended.
DMSO : 42.4 mg/mL (100.11 mM), Sonication is recommended.
KeywordsVHL | STF-31 | STF31 | STF 31 | RCC4/VHL | RCC4 | inhibitor | inhibit | GLUT1 | GLUT | Glucose transporter | glucose | Autophagy
Inhibitors RelatedStavudine | Aceglutamide | Hemin | Tamoxifen | Cysteamine hydrochloride | Guanidine hydrochloride | Hydroxychloroquine | Enzalutamide | Paeonol | Naringin | Alginic acid | Sildenafil citrate
Related Compound LibrariesTarget-Focused Phenotypic Screening Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Obesity Compound Library | Glutamine Metabolism Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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