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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>STO-609
STO-609
  • STO-609

STO-609 NEW

Price $35 $81 $129
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: STO-609 CAS No.: 52029-86-4
Purity: 97.79% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameSTO-609
DescriptionSTO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL).
In vitroSTO-609 also inhibits their autophosphorylation activities. STO-609 is highly selective for CaM-KK without any significant effect on the downstream CaM kinases (CaM-KI and -IV), and the IC50 value of the compound against CaM-KII is 10 μg/mL. STO-609 inhibits constitutively active CaM-KKα as well as the wild-type enzyme. In transfected HeLa cells, STO-609 dose-dependently suppresses the Ca2+-induced activation of CaM-KIV. STO-609 (1μg/mL) significantly reduces the endogenous activity of CaM-KK in SH-SY5Y neuroblastoma cells (80%).
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 15 mg/mL (47.73 mM), Sonication is recommended.
KeywordsSTO-609 | STO609 | Inhibitor | inhibit | CaM-KKβ | CaM-KKα | CaMK | Calmodulin-dependent protein kinases | Calmodulin-dependent kinases | Autophagy | AMPK | AMP-activated protein kinase
Inhibitors RelatedStavudine | Aceglutamide | Hemin | Tamoxifen | Cysteamine hydrochloride | Guanidine hydrochloride | Hydroxychloroquine | Paeonol | Naringin | Alginic acid | Chitosan oligosaccharide | Sildenafil citrate
Related Compound LibrariesGlycometabolism Compound Library | Bioactive Compound Library | Antidepressant Compound Library | Neuronal Signaling Compound Library | Kinase Inhibitor Library | Glutamine Metabolism Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Neuronal Differentiation Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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