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Postion:Product Catalog >API>Digestive system drugs>Antacid and Mucosal protective Drugs>Sucralfate
Sucralfate
  • Sucralfate

Sucralfate NEW

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Package 1removed
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: Sucralfate CAS No.: 54182-58-0
Supply Ability: 10g Release date: 2026/04/22

Product Introduction

Bioactivity

NameSucralfate
DescriptionSucralfate (Sucrose octasulfate–aluminum complex) is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
Cell ResearchSucralfate is dissolved or suspended in culture medium containing 20% FBS. Cells are incubated with the agent at 37°C under 5% CO2, in air for 0.5-4 h. In some cases, cells are treated with 10-5mol/L indomethacin for 4h before the addition of the agent to determine whether or not intracellular prostaglandins are involved in the protective mechanisms of sucralfate. (Only for Reference)
In vitroSucralfate may inhibit intestinal epithelial motility by sterically interfering with adhesion to collagen I[3]. It protects RGMl cells from acid- and pepsin-induced damage[4].
In vivoThe protective effects of sucralfate against ARC(acute radiation colitis) may be partially due to the supression of radiation-induced apoptosis by way of p53 in the colon and the protection of the colonic epithelial stem cell region[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 20.87 mg/mL (10 mM)
H2O : 0.4 mg/mL (0.19 mM), when pH is adjusted to 2 with HCl. Sonication is recommended.
KeywordsSucrose octasulfate-aluminum complex | Sucralfate | ProstaglandinReceptor | Prostaglandin Receptor | PGF | Pepsin | Inhibitor | inhibit | Fibrinogen chain | FGF2 | Bacterial
Inhibitors RelatedNeomycin sulfate | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Ferulic Acid | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES
Related Compound LibrariesAnti-COVID-19 Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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