Sulfanilamide NEW
| Price | $53 |
| Package | 5g |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: Sulfanilamide | CAS No.: 63-74-1 |
| Purity: 99.76% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | Sulfanilamide |
| Description | Sulfanilamide (UK-124) can competitively inhibit bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM. |
| In vitro | Sulfanilamide was able to inhibit a recombinant yeast strain with a wild-type FOL1 gene with an IC50 of 286.8 μg/mL, but a single mutation in the active region of the fungal dihydropyrimidine synthase from 55Trp to 55Ala or 57Pro to 57Ser resulted in resistance to Sulfanilamide with an IC50 >800 μg/mL. /The sulfonamide group of Sulfanilamide inhibits dihydropyridine synthase purified from E. coli. p-Aminobenzoic acid synthesis is used for essential folic acid in the synthesis of purines, pyrimidines, and other amino acids. The IC50 of Sulfanilamide was 320 μM for dihydropyridine synthase, and the Km was 2.5 uM for PABA. Sulfanilamide was able to inhibit the growth of Plasmodium falciparum-containing pKOS-pfPPPK-DHPS(His) bacterial cells to a certain extent with an IC50 of 380 uM. |
| In vivo | Sulfanilamide was able to inhibit a recombinant yeast strain with a wild-type FOL1 gene with an IC50 of 286.8 μg/mL, but a single mutation in the active region of the fungal dihydropyrimidine synthase from 55Trp to 55Ala or 57Pro to 57Ser resulted in resistance to Sulfanilamide with an IC50 >800 μg/mL. /The sulfonamide group of Sulfanilamide inhibits dihydropyridine synthase purified from E. coli. p-Aminobenzoic acid synthesis is used for essential folic acid in the synthesis of purines, pyrimidines, and other amino acids. The IC50 of Sulfanilamide was 320 μM for dihydropyridine synthase, and the Km was 2.5 uM for PABA. Sulfanilamide was able to inhibit the growth of Plasmodium falciparum-containing pKOS-pfPPPK-DHPS(His) bacterial cells to a certain extent with an IC50 of 380 uM. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 260 mg/mL (1509.87 mM), Sonication is recommended. H2O : 11.06 mg/mL (64.23 mM), Sonication is recommended. Ethanol : 14 mg/mL (81.3 mM), Sonication is recommended. 10% DMSO+90% Saline : 10 mg/mL (58.07 mM), Solution. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (11.61 mM), Sonication is recommended. |
| Keywords | UK124 | UK 124 | Sulfanilamide | Inhibitor | inhibit | DHPS | Bacterial | Antibiotic |
| Inhibitors Related | Neomycin sulfate | Aceglutamide | Hemin | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Sulfamethoxazole sodium | Terbinafine hydrochloride | Hydroxychloroquine | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate |
| Related Compound Libraries | Bioactive Compound Library | Autophagy Compound Library | Drug Repurposing Compound Library | Drug-Fragment Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Drug Metabolite/Impurity Library | Anti-Infection Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:110952-90-4
-
-
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
|
VIP6Y
|
WUHAN FORTUNA CHEMICAL CO., LTD
|
2026-06-25 | ||
|
VIP6Y
|
RongNa Biotechnology Co.,Ltd
|
2026-06-24 | ||
|
VIP2Y
|
Shaanxi Xianhe Biotech Co., Ltd
|
2026-06-23 | ||
| $53.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-06-02 | |
| $53.00 |
VIP2Y
|
TargetMol Chemicals Inc.
|
2026-06-02 | |
| $10.00 |
VIP6Y
|
Hebei Chuanghai Biotechnology Co,.LTD
|
2026-05-28 | |
| $10.00 |
Hebei Chuanghai Biotechnology Co., Ltd
|
2026-03-20 | ||
|
Moxin Chemicals
|
2025-12-16 | |||
|
Hebei Chuanghai Biotechnology Co., Ltd
|
2025-06-27 | |||
| $10.00 |
Hebei Zhuanglai Chemical Trading Co Ltd
|
2025-05-23 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY