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Postion:Product Catalog >sulfopin
sulfopin
  • sulfopin

sulfopin NEW

Price $30 $40 $64
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: sulfopin CAS No.: 2451481-08-4
Purity: 99.99% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

Namesulfopin
DescriptionSulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
In vitroSulfopin (2μM, HEK293 cells, 48 hours) downregulates Myc transcription. Sulfopin (1μM, 2.5μM, PATU-8988T cells, 4 days) shows a significant reduction in the member of synthesis (S)-phase cells and a corresponding increase of growth 1 (G1)-phase cells.[1]
In vivoSulfopin (40mg/kg, p.o., bis in die/qualer in die for 7 days) regresses neuroblastoma in mice. Sulfopin (20-40mg/kg, i.p., daily for days) inhibits pancreatic cancer progression in mice.[1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 125 mg/mL (443.58 mM), Sonication is recommended.
10% DMSO+90% Saline : 10 mg/mL (35.49 mM), Solution.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (11.71 mM), Sonication is recommended.
Keywordstumors | sulfopin | PIN1-3 | Pin1 | pancreatic | neuroblastoma | Inhibitor | inhibit | HEK293 | cells | cancer | antiproliferative
Related Compound LibrariesHighly Selective Inhibitor Library | Bioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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