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Postion:Product Catalog >SUN 1334H
SUN 1334H
  • SUN 1334H

SUN 1334H NEW

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Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: SUN 1334H CAS No.: 607736-84-5
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameSUN 1334H
DescriptionSUN 1334H is a potent, orally active, and highly selective H1 receptor antagonist with a Ki of 9.7 nM.
In vitroIn CHO-K1/hERG cells,SUN-1334H causes potent inhibition of histamine induced contractions of isolated guinea-pig ileum(IC50 : 0.198 μM)[2].
In vivoIn beagle dogs and in ovalbumin-induced rhinitis in guinea pigs, SUN-1334H potently inhibits histamine-induced bronchospasm for 24 hours following oral administration and completely suppresses histamine-induced skin wheal [1]. SUN-1334H significantly reduces passive and active cutaneous anaphylactic reactions in skin allergy models. In central nervous system side effect models, SUN-1334H, desloratadine, and fexofenadine show no significant effects [2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsSUN 1334H | HistamineReceptor | Histamine Receptor | H1 receptor
Inhibitors RelatedUndecane | Betahistine mesylate | Histamine dihydrochloride | Meclizine dihydrochloride | Lidocaine | Famotidine | Sodium butanoate | Nizatidine | Alginic acid | Mianserin hydrochloride | Trazodone hydrochloride | Doxepin hydrochloride

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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