Product Details
| Product Name:
Tanimilast |
CAS No.:
1239278-59-1 |
| Purity:
99.18% |
Supply Ability:
10g |
| Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | Tanimilast |
| Description | Tanimilast (CHF-6001) is a novel, potent, and selective phosphodiesterase 4 inhibitor with an IC50 value of 0.026 ± 0.006 nM. It exhibits potent anti-inflammatory activity and is indicated for topical use in the lungs. Tanimilast was studied for its effects on obstructive lung disease. |
| In vitro | Methacholine-induced protein expression of smooth muscle-myosin was fully inhibited by CHF-6001 (0.3-100 nM; Guinea pig precision-cut lung slices). CHF-6001 did not affect airway closure and had limited effects on TGF-β1-induced remodeling, but rather, it inhibited methacholine-induced TGF-β release.[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (72.72 mM), Sonication is recommended.
|
| Keywords | Tanimilast | PDE4 | CHF6001 | CHF 6001 |
| Inhibitors Related | Kaolin | Rhamnose monohydrate | Gum arabic | Kojic acid | D(+)-Raffinose pentahydrate | Hydroxypropyl Cellulose | 1,8-Cineole | 1,4-Naphthoquinone | Ethyl linoleate | D-Psicose | Gluconate Calcium | Sildenafil citrate |
| Related Compound Libraries | NF-κB Signaling Compound Library | Bioactive Compound Library | ReFRAME Related Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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VIP2Y
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Shaanxi Dideu New Materials Co. Ltd
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2026-06-30 |
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VIP2Y
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Shaanxi Dideu New Materials Co. Ltd
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2026-06-30 |
United States