TC ASK 10 NEW
| Price | $29 | $83 | $133 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: TC ASK 10 | CAS No.: 1005775-56-3 |
| Purity: 99.86% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | TC ASK 10 |
| Description | TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1,IC50 = 14 nM). The IC50 value for ASK2 is 0.51 μM. |
| In vitro | Streptozotocin (STZ)-induced JNK in INS-1 pancreatic β cells from 0.3 μM inhibited by TC ASK 10 (0-10 μM; 1 hour; INS-1 cells). Phosphorylation of p38 is also inhibited in a dosedependent manner. |
| In vivo | In rats, Pharmacokinetic profiles are tested. TC ASK 10 (rat cassette doing at 0.1 mg/kg, iv and 1 mg/kg, po.) has a good oral bioavailability. The Cmax, Tmax and AUCpo,0-8h are 285.1 ng/mL, 1.67 h and 275.4 ng.h/mL, respectively for TC ASK 10. |
| Storage | Keep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (9.25 mM), Sonication is recommended. DMSO : 100 mg/mL (231.29 mM), Sonication is recommended. |
| Keywords | TC ASK-10 | TC ASK10 | TC ASK 10 | selective | Phosphorylation | pharmacokinetic | p38 | oral | MAP3K | MAP kinase kinase kinase, MEKK, MAPKKK | JNK | Inhibitor | inhibit | bioavailability | ASK2 | ASK1 | Apoptosis |
| Inhibitors Related | Stavudine | Aceglutamide | Adenosine | Urea | Tamoxifen | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Dextran sulfate sodium salt (MW 5000) | Sildenafil citrate |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Reprogramming Compound Library | Pain-Related Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Kinase Inhibitor Library | Pyroptosis Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2780.00 |
VIP3Y
|
TargetMol Chemicals Inc.
|
2026-07-14 | |
| $95.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-07-14 | |
| $20.00 |
VIP2Y
|
Ningbo Qingteng Plastic Cost.,Ltd.
|
2026-08-10 | |
| $29.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-07-27 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY