Product Details
| Product Name:
TES-1025 |
CAS No.:
1883602-21-8 |
| Purity:
98.81% |
Supply Ability:
10g |
| Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | TES-1025 |
| Description | TES-1025 is an effective and selective inhibitor of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (IC50: 13 nM). |
| In vitro | TES-1025 increases NAD+ levels in cellular systems[1]. |
| In vivo | TES-1025 (0.5 mg/kg; i.v.) shows low blood clearance, with low volumes of distribution and half-lives of about 5.33 h, although the blood concentration of TES-1025 (5 mg/kg) is quantifiable for up to 8 h after oral administration. A good systemic exposure is recorded for TES-1025, with a Cmax of 2570 ng/mL reaches at 2 h. The greater oral exposure of TES-1025 is AUC0-8h of 19?200 h?ng/mL and 36?600 h?ng/mL, respectively[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 95 mg/mL (247.76 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (8.61 mM), Sonication is recommended.
|
| Keywords | TES-1025 | TES1025 | TES 1025 | Inhibitor | inhibit | human ACMSD | ACMSD |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States