Tetracycline NEW
| Price | $29 |
| Package | 1g |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Tetracycline | CAS No.: 60-54-8 |
| Purity: 92.65% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Tetracycline |
| Description | Tetracycline is an orally active broad-spectrum antibiotic that exhibits inhibitory activity against various Gram-positive and Gram-negative bacteria, as well as Chlamydia, Mycoplasma, and Rickettsia. It is commonly used in anti-infection research and can also be used to induce tumor regression based on BCR-ABL gene silencing. |
| In vitro | METHODS: Neuroblastoma cells were treated with Binimetinib (0-2 μM) for 24-120 h. Cell viability was measured by MTT assay. RESULTS: Four cell lines, CHP-212, SK-N-BE, SK-N-AS and SJ-NB-10, were sensitive to Binimetinib, achieving <50% survival after 24-120 h of treatment, while five cell lines were resistant to the drug. [1] METHODS: NSCLC cells A549, H157 and H522 were treated with Binimetinib (0.5-1 μM) for 48 h. Cell cycle was measured by flow cytometry. RESULTS: Binimetinib induced G1 phase block in three sensitive NSCLC cell lines at relatively low concentration ranges, e.g. 0.5 and 1 μM. [2] |
| In vivo | METHODS: To detect in vivo antitumor activity, Binimetinib (5 mg/kg) and BMK120 (7.5 mg/kg) were administered by gavage to athymic (nu/nu) mice bearing A549 xenografts once daily for 21 days. RESULTS: Binimetinib and BKM120 alone at the doses tested only weakly inhibited the growth of A549 xenografts, but the combination of Binimetinib and BKM120 significantly inhibited the growth of A549 xenografts. [2] |
| Storage | Powder: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 15 mg/mL (33.75 mM), Solution. DMSO : 262.5 mg/mL (590.64 mM), Sonication is recommended. |
| Keywords | Tetracycline | oral | Major prion protein | Inhibitor | inhibit | broad-spectrum | Bacterial | Antibiotic | 30S ribosome | 16S ribosome |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | Kanamycin sulfate | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Sodium diacetate | Sodium bicarbonate | BES |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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