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Postion:Product Catalog >TM-38837
TM-38837
  • TM-38837

TM-38837 NEW

Price $8 $6 $2
Package 1kg 100kg 1000kg
Min. Order: 1kg
Update Time: 2026-07-09

Product Details

Product Name: TM-38837 CAS No.: 1253641-65-4
Min. Order: 1kg Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2026/07/09
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
Contact person: Jessica

1. Product information

Names

NameTM-38837
SynonymMore Synonyms

 TM 38837 Biological Activity

DescriptionTM38837 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist. TM38837 shows limited penetrance to the brain in order to minimize or prevent CNS adverse reactions, and preserves potential antiobesity effects. TM38837 reduces propensity for psychiatric side effects[1][2].
Related Catalog
Research Areas >> Metabolic Disease
Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target

CB1

In VivoTM38837 (10-100 mg/kg; p.o.) induces a significant increase in freezing behavior at 100 mg/kg[1]. Animal Model: 7-8 weeks old male C57BL/6 N mice (B6N)[1] Dosage: 10, 30, or 100 mg/kg Administration: p.o. Result: High dose (100 mg/kg) induced a significant increase in freezing behavior.
References

[1]. Micale V, et al. The Cannabinoid CB1 Antagonist TM38837 With Limited Penetrance to the Brain Shows ReducedFear-Promoting Effects in Mice. Front Pharmacol. 2019 Mar 20;10:207.

[2]. Klumpers LE, et al. Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects. Br J Clin Pharmacol. 2013 Dec;76(6):846-57.

 Chemical & Physical Properties

Density1.4±0.1 g/cm3
Molecular FormulaC30H25Cl2F3N4OS
Molecular Weight617.512
Exact Mass616.107849
LogP8.91
Index of Refraction1.635


2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


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3. Shipping

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4. Contact information

For more details, pls contact us freely.

Mob: 86 17630978909

WhatsApp/Skype/Wechat/LINE: 86 17630978909

Company Profile Introduction

Henan Fengda Chemical Co., Ltd. a research customization and supplier specializing in PPb grade ultra-high purity electronic chemicals, deeply rooted in the semiconductor and new display fields, committed to providing the most core and purest chemical components for photoresist and high-end display materials. We provide key monomers for KrF/ArF photoresist, photoacid generators (PAGs), photoacids, and etching solution raw materials, providing cornerstone materials for advanced process photoresist formulations; We take ICP-MS full spectrum metal impurity analysis as the quality cornerstone and provide ICP-MS metal impurity COA reports to meet the strict industry requirements for PPb grade electronic chemical materials. The COA report contains important data such as NA, Mg, K, Ca, Al, Cr, Fe, Ni, Cu, Zn, Pb, Ag, etc. To provide customers with pure and reliable source assurance for cutting-edge research and stable production.

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