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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>TMC353121
TMC353121
  • TMC353121

TMC353121 NEW

Price $149
Package 2mg
Supply Ability: 10g
Update Time: 2026-07-27

Product Details

Product Name: TMC353121 CAS No.: 857066-90-1
Purity: ≥98% Supply Ability: 10g
Release date: 2026/07/27

Product Introduction

Bioactivity

NameTMC353121
DescriptionTMC353121 is a respiratory syncytial virus (RSV) fusion inhibitor with anti-RSV activity that inhibits the production of the inflammatory cytokines TNF-α, IL-6, and IL-1β, as well as chemokines, KC, IP-10, MCP, and MIP1-α.
In vitroTMC353121 is an effective RSV fusion inhibitor, active against wild-type RSV (strain LO) with a 50% effective concentration (EC50) of 0.07 ng/mL in HeLaM cells[2].
In vivoAfter single subcutaneous administration and repeated administration 24 hours post-intranasal RSV inoculation, TMC353121 dose-dependently reduces viral titers in bronchoalveolar lavage fluid[2].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.58 mM), Sonication is recommended.
DMSO : 30 mg/mL (53.7 mM), Sonication is recommended.
KeywordsTNF-α | TMC-353121 | TMC353121 | TMC 353121 | RSV | ILReceptor | IL-6 | IL Receptor
Inhibitors RelatedKaolin | Fluorene | Undecane | Acetylcysteine | Gum arabic | Triphenyl phosphate | 1,8-Cineole | Dodecane | Tributyrin | Glucosamine | Diallyl disulfide | Perflubron

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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