Product Details
| Product Name:
Topterone |
CAS No.:
60607-35-4 |
| Purity:
100.00% |
Supply Ability:
10g |
| Release date:
2026/07/27 |
Product Introduction
Bioactivity
| Name | Topterone |
| Description | Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone in castrated immature male hamsters. |
| In vivo | To determine its endocrine profile, Topterone is administered parenterally or topically to rats, rabbits, or hamsters. Systemic administration reveals that Topterone exhibits both antiandrogenic and progestational effects. However, topical application at a dose of 1 g/kg/day fails to induce a systemic antiandrogenic response, and only a minimal progestational response is observed at 32 mg/kg/day. No other endocrine activities are detected in these experiments[2].
Topterone demonstrates the inhibition of flank organ development in castrated immature male hamsters in response to both testosterone and dihydrotestosterone, whereas Progesterone inhibits stimulation by only testosterone. Furthermore, topical application of Topterone has been shown to cause regression in the development of the flank organ[1]. |
| Storage | Store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Topterone | AndrogenReceptor | Androgen Receptor | Androgen |
| Inhibitors Related | Dehydroisoandrosterone 3-acetate | Bicalutamide | 2-Ethylhexyl trans-4-methoxycinnamate | 6-Amino-5-bromoquinoxaline | S-23 | Enzalutamide | Octinoxate | Allura Red AC | Sunset Yellow FCF | Ostarine | 2-sec-Butylphenol | Flutamide |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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