trans-Pralsetinib NEW
| Price | $64 |
| Package | 2mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-22 |
Product Details
| Product Name: trans-Pralsetinib | CAS No.: 2097132-93-7 |
| Purity: 98.06% | Supply Ability: 10g |
| Release date: 2026/04/22 |
Product Introduction
Bioactivity
| Name | trans-Pralsetinib |
| Description | trans-Pralsetinib (trans-BLU-667) is a potent inhibitor of the RET (Rearranged during Transfection) kinase. This compound originates from Compound Example 129 in patent US20170121312A1. RET is a receptor tyrosine kinase whose genetic rearrangements or mutations are key drivers in various cancers, including non-small cell lung cancer (NSCLC) and medullary thyroid cancer. By inhibiting RET kinase activity, trans-Pralsetinib blocks downstream oncogenic signaling pathways, thereby exerting anti-tumor effects. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (149.93 mM), Sonication is recommended. |
| Keywords | transPralsetinib | trans Pralsetinib | RET | cRET | cis-Pralsetinib | cis-BLU-667 | cis-BLU667 | cis-BLU 667 |
| Inhibitors Related | Regorafenib monohydrate | Regorafenib Hydrochloride | KBP-7018 | TG-89 | Tafetinib | Regorafenib | DUN73423 | AST 487 | Amuvatinib | Lenvatinib mesylate | Lenvatinib | Selpercatinib |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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