TREM2 agonist-2 NEW
| Price | $283 | $698 | $1160 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-28 |
Product Details
| Product Name: TREM2 agonist-2 | CAS No.: 2738485-98-6 |
| Purity: 99.71% | Supply Ability: 10g |
| Release date: 2026/05/28 |
Product Introduction
Bioactivity
| Name | TREM2 agonist-2 |
| Description | TREM2 agonist-2 (I-192) is an orally efficient small molecule agonist specifically targeting TREM2, serving as a highly potent triggering receptor expressed on myeloid cells 2 (TREM2) agonist, employed in neurodegenerative disease research. |
| In vitro | Methods:Cell viability assays were performed, with HEK293 cells treated with TREM2 agonist-2 (0-100 μM) for 16 hours. Results: Agonist-2 activated hTREM2 with an EC50 value of less than 0.05 μM. [1] |
| In vivo | Methods: In mouse models, TREM2 agonist-2 (50 mg/kg, twice daily for one day) was administered via oral gavage. Results: Agonist-2 treatment promoted the binding of TREM2 to microglia. [1] |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 257.5 mg/mL (569.79 mM), Sonication is recommended. |
| Keywords | TREM2 |
| Related Compound Libraries | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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