Troleandomycin NEW
| Price | $499 | $599 |
| Package | 1mg | 2mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-25 |
Product Details
| Product Name: Troleandomycin | CAS No.: 2751-09-9 |
| Purity: 98.00% | Supply Ability: 10g |
| Release date: 2026/05/25 |
Product Introduction
Bioactivity
| Name | Troleandomycin |
| Description | Troleandomycin (Triacetyloleandomycin), a macrolide antibiotic, is an orally active and specific CYP3A inhibitor that induces mnemonic speech, induces prolonged cholestasis, and can be used in the study of asthma. |
| In vitro | Troleandomycin significantly inhibits microsomal side chain hydroxylation in mouse and human livers in a dose-dependent manner. [1] |
| In vivo | Troleandomycin significantly inhibits the 6β-hydroxylation of testosterone, the 25- and 26-hydroxylation of 5β-cholestane-3α, 7α, and 12α-triol, and the 23R-, 24R-, 24R-, 5β-cholestane-3α, 7α 24S- and 27-hydroxylation, 12α, 25-tetrol in recombinant CYP3A4 and microsomes, but the IC50 value of microsomes is slightly higher than that of recombinant CYP3A4.[2] |
| Storage | Store at low temperature,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (2.46 mM), Sonication is recommended. DMSO : 50 mg/mL (61.43 mM), Sonication is recommended. |
| Keywords | Troleandomycin | CYP3A | Antibiotic |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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