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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Trolox
Trolox
  • Trolox

Trolox NEW

Price $42
Package 500mg
Supply Ability: 10g
Update Time: 2026-04-21

Product Details

Product Name: Trolox CAS No.: 53188-07-1
Purity: 99.90% Supply Ability: 10g
Release date: 2026/04/21

Product Introduction

Bioactivity

NameTrolox
DescriptionTrolox is a vitamin E analogue, used in reducing oxidative stress or damage.
In vitroMETHODS: Human cervical cancer cells HeLa were treated with Trolox (2.5-160 μM) for 24 h and cell viability was measured using MTT assay. RESULTS: Cell viability decreased dose-dependently, with the maximum effect observed at 160 μM Trolox. [1] METHODS: Human skin fibroblasts were treated with Trolox (0.5 mM) for 96 h. The expression levels of target proteins were measured by Western Blot. RESULTS: Trolox increased the mitochondrial levels of Mfn2 in primary human skin fibroblasts without affecting these levels of Drp1 and hFis1. [2]
In vivoMETHODS: To investigate the neuroprotective effects, Trolox (50 mg/kg) was intraperitoneally injected once a day for ten days into an MPTP-induced Parkinson's disease mouse model. RESULTS: Trolox may exert neuroprotective effects on dopaminergic neurons against MPTP-induced oxidative stress, neuroinflammation, motor dysfunction and neurodegeneration. [3]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (19.98 mM), Solution.
DMSO : 50 mg/mL (199.77 mM), Sonication is recommended.
KeywordsTrolox | ReactiveOxygenSpecies | Reactive Oxygen Species | Inhibitor | inhibit | Ferroptosis | Apoptosis | Antioxidant
Inhibitors RelatedEthoxyquin | Kaolin | Stavudine | Aceglutamide | Allopurinol | Hemin | Urea | Tamoxifen | Metronidazole | Ethyl linoleate | Formamide | Alginic acid
Related Compound LibrariesBioactive Compound Library | Antidepressant Compound Library | Antioxidant Compound Library | Pyroptosis Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Oxidation-Reduction Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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