Product Details
| Product Name:
TTP-8307 |
CAS No.:
950225-08-8 |
| Purity:
99.14% |
Supply Ability:
10g |
| Release date:
2025/06/03 |
Product Introduction
Bioactivity
| Name | TTP-8307 |
| Description | TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses, and inhibits coxsackievirus B3 and poliovirus by interfering with viral RNA synthesis.TTP-8307 can be used in the study of viral infections. |
| In vitro | TTP-8307 targeted non-structural protein 3A and inhibited the replication of enterovirus B3 (CVB3 Nancy) with an EC50 of 1.2 μM. In addition, TTP-8307 inhibited the replication of three Sabin poliovirus strains, as well as enteroviruses A16 and A21, with EC50s of 0.85 and 5.34 μM, respectively.Meanwhile, TTP-8307 inhibited the replication of human rhinoviruses (HRVs) 2, 29, 39, 45, 63 and 85 was also inhibitory. Mutations in non-structural protein 3A caused resistance to TTP-8307, a novel enterovirus replication inhibitor.
In addition, TTP-8307 inhibits OSBP-dependent viruses, including encephalomyelitis virus (EMCV) and hepatitis C virus (HCV). [1][2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 80 mg/mL (183.28 mM), Sonication is recommended.
|
| Keywords | TTP-8307 | TTP 8307 | RNASynthesis | RNA Synthesis | HCVProtease | HCV Protease | HCV | DNASynthesis | DNA/RNA SynthesisProtease | DNA Synthesis |
| Inhibitors Related | 5-Fluorouracil | Procaine | Methyl 2-amino-5-bromobenzoate | Rifaximin | Ribavirin | Guanidine hydrochloride | N-Nitrosodiethylamine | Artemisinin | Cytarabine | Thymidine | Temozolomide | Folic acid |
| Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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