Product Details
| Product Name:
TUG-424 |
CAS No.:
1082058-99-8 |
| Purity:
99.77% |
Supply Ability:
10g |
| Release date:
2026/04/20 |
Product Introduction
Bioactivity
| Name | TUG-424 |
| Description | TUG-424 significantly enhances glucose-stimulated insulin secretion at 100 nM. TUG-424 is a potent and selective free fatty acid receptor 1 agonist (EC50: 32 nM). |
| In vitro | At equivalent glucose concentrations, TUG-424's roughly double enhancement of secretion in the context of 12 mM glucose parallels the effect triggered by palmitate. Increasing TUG-424 doses (100 nM to 10 μM) significantly boost glucose-stimulated insulin secretion, beginning notably at 100 nM and peaking at 3 μM. Additionally, TUG-424 slightly yet significantly diminishes basal insulin secretion at 2.8 mM glucose [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (189.16 mM), Sonication is recommended.
|
| Keywords | TUG-424 | TUG 424 | FFA1/GPR40 |
| Inhibitors Related | Monomethyl fumarate | Kynurenic acid | Pamoic acid disodium | Azathioprine | CRTh2 antagonist 2 | Fezagepras sodium | Benzyl nicotinate | 1-methoxycyclopropanecarboxylic acid | TUG-1375 | CAY10595 | Timapiprant | Tricosanoic acid |
| Related Compound Libraries | Bioactive Compound Library | Anti-Diabetic Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$58.00
|
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-06-15 |
|
|
$2800.00
|
VIP2Y
|
TargetMol Chemicals Inc.
|
2026-05-11 |
|
|
$1.00
|
VIP7Y
|
Career Henan Chemical Co
|
2019-12-26 |
United States