TWS-119 TFA NEW
| Price | $1520 | $1980 |
| Package | 25mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: TWS-119 TFA | CAS No.: 1507095-58-0 |
| Purity: 99.65% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | TWS-119 TFA |
| Description | TWS-119 TFA is a potent GSK-3β inhibitor and Wnt/β-catenin activator. TWS-119 TFA induces neuronal differentiation, enhances T-cell antitumor activity, and protects the BBB in stroke models. |
| In vitro | TWS-119 TFA sctivated mTOR, upregulated Bcl-2, and inhibited Caspase-3 in γδT cells (<4 μM). Increased Granzyme B (0.5-2 μM) to boost cytolytic activity[2]. |
| In vivo | In rtPA-treated MCAO rats, i.p. injection TWS-119 TFA (30 mg/kg) activated Wnt/β-Catenin signaling, reduced edema, and lowered BBB permeability[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : < 1 mg/mL (insoluble) DMSO : 40 mg/mL (73.21 mM), Sonication is recommmended. |
| Keywords | TWS-119 | TWS 119 | FK-906 hydrochloride | FK906 hydrochloride | FK-906 HCl | FK906 HCl | FK 906 hydrochloride |
| Inhibitors Related | Chlorquinaldol | Urea | Cromolyn sodium | Kirenol | Indazole | 4-Chloro-2'-bromoacetophenone | Neohesperidin | Ethyl linoleate | Monensin sodium salt | (±)-Nornicotine | GSK-3 Inhibitor 5 | Methyl Vanillate |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
-
-
CAS:1259384-47-8
-
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $181.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-05-11 | |
|
VIP1Y
|
Guangzhou Xijia New Materials Co.,Ltd
|
2026-05-16 | ||
| $5.00 |
VIP2Y
|
Hebei Jiafan Trading Company Limited
|
2026-06-18 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY