UCT943 NEW
| Price | $106 | $160 | $273 |
| Package | 1mg | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: UCT943 | CAS No.: 1450666-80-4 |
| Purity: 99.87% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | UCT943 |
| Description | UCT943 is an inhibitor of Plasmodium falciparum PI4K (IC50 = 23 nM). |
| In vitro | UCT943 maintains a high degree of selectivity (>200-fold) for parasite PI4K versus human PI4Kβ isoenzyme (IC50 = 5.4 μM) in vitro, and its inhibition is associated with immunosuppressive effects[1]. |
| In vivo | In vivo, UCT943 shows good efficacy in the Plasmodium vivax (3-10 mg/kg; orally) and P. falciparum NSG mouse models (0.01-10 mg/kg; orally). UCT943 (10 mg/kg; p.o.) reduces parasitemia by >99.9% in the mouse P. berghei infection model and cures all mice (MSD>30)[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 200 mg/mL (467.92 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (11.7 mM), Sonication is recommended. |
| Keywords | UCT-943 | UCT943 | UCT 943 | PvPI4K | PI4K | Parasite |
| Inhibitors Related | Flubendazole | Gum arabic | Kojic acid | Urethane | Hydroxychloroquine | Metronidazole | 2-Amino-2-methyl-1-propanol | Doxycycline | Fenpyroximate | Methylene Blue trihydrate | Coumaran | Benzimidazole |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Autophagy Compound Library | Anti-Ovarian Cancer Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library | Neuronal Differentiation Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $106.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-07-14 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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