Vaborbactam NEW
| Price | $339 |
| Package | 2mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-01 |
Product Details
| Product Name: Vaborbactam | CAS No.: 1360457-46-0 |
| Purity: 98.81% | Supply Ability: 10g |
| Release date: 2026/06/01 |
Product Introduction
Bioactivity
| Name | Vaborbactam |
| Description | Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections. |
| In vitro | The β-lactamase inhibitor vaborbactam can also form an acyl-enzyme complex with Pseudomonas aeruginosa PBP3. We found that vaborbactam inhibits PBP3 (IC50 of 262 μM), and its binding to PBP3 increases the protein thermal stability by about 2°C[1]. |
| In vivo | In a neutropenic mouse thigh infection model, the administration of 100 mg/kg meropenem alone and in combination with various doses of vaborbactam against Klebsiella pneumoniae was evaluated. The results showed that intraperitoneal injection of 300 mg/kg meropenem combined with 50 mg/kg vaborbactam resulted in the greatest reduction in bacterial counts compared to the untreated control group[2]. |
| Storage | Store at low temperature,Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 2 mg/mL (6.73 mM), Sonication is recommended. |
| Keywords | β-Lactamase | Vaborbactam | RPX-7009 | RPX 7009 |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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