VAF347 NEW
| Price | $34 | $47 | $77 |
| Package | 1mg | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-26 |
Product Details
| Product Name: VAF347 | CAS No.: 574759-62-9 |
| Purity: 99.55% | Supply Ability: 10g |
| Release date: 2026/05/26 |
Product Introduction
Bioactivity
| Name | VAF347 |
| Description | VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects. |
| In vitro | In HL-60 cells, VAF347 augments retinoic acid-induced expression of AhR, Lyn, Vav1, and c-Cbl as well as p47phox. Several interactions of the partners in the signal body appear to be enhanced: Fgr interacts with c-Cbl, CD38, and pS259c-Raf, and AhR interacts with c-Cbl and Lyn[1]. VAF347 enhances retinoic acid-induced cell cycle arrest[1]. |
| In vivo | AhR-deficient mice are resistant to VAF347's ability to block allergic lung inflammation in vivo[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 17.85 mg/mL (51.04 mM), Sonication is recommended. 10% DMSO+90% Corn Oil : 1.5 mg/mL (4.29 mM), Sonication is recommended. |
| Keywords | VAF-347 | VAF347 | VAF 347 | Inhibitor | inhibit | ArylHydrocarbonReceptor | Aryl hydrocarbon receptor | AhR |
| Inhibitors Related | Diosmin | Sudan IV | 2-Mercaptobenzothiazole | 5,6-Benzoflavone | Benzyl butyl phthalate | 1-Hydroxypyrene | Skatole | L-Kynurenine | Indole-3-carbinol | MeBIO | DiMNF | Dibenzothiophene |
| Related Compound Libraries | Bioactive Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
![[Ala107]-MBP (104-118) acetate](https://img.chemicalbook.com/ProductImageEN2/2025-11/Large/3ce64816-d784-47e0-be06-15fc6f540279.png)
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $34.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-05-26 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY