Verapamil hydrochloride NEW
| Price | $41 |
| Package | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: Verapamil hydrochloride | CAS No.: 152-11-4 |
| Purity: 99.79% | Supply Ability: 10g |
| Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | Verapamil hydrochloride |
| Description | Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent. |
| Cell Research | Verapamil is dissolved in DMSO and stored, and then diluted with appropriate media before use[1]. Cells (1×105) are treated with 10 nM Bortezomib and/or 70 μM Verapamil for 16 hours and incubated for another 4 hours with Alamar-Blue. Activity of the mitochondrial dehydrogenase results in conversion of the coloring, which is followed by measurement of the absorption using a spectrophotometer[1]. |
| In vitro | Verapamil exhibits antiarrhythmic properties, reduces myocardial oxygen consumption in rats, and preserves Cx43 protein. |
| In vivo | Verapamil and Diltiazem essentially inhibit the hydrolase activity of recombinant CES2, with inhibition constants (Ki) of 0.25 ± 0.02 μM and 3.84 ± 0.99 μM, respectively. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (101.82 mM), Sonication is recommended. H2O : 24.6 mg/mL (50.1 mM), Sonication is recommended. |
| Keywords | Verapamil hydrochloride | Verapamil Hydrochloride | Verapamil hydrochlorid | Verapamil | pressure | P-gp?(P-glycoprotein) | P-gp | Pgp | P-glycoprotein | Palbociclib | Multidrug resistance protein 1 | MDR1 | lysosomotropic | Inhibitor | inhibit | high | Cytochrome P450 | CYPs | CYP3A4 | Cluster of differentiation 243 | CD243 | CalciumChannel | Calcium Channel | Calcan Hydrochloride | Ca2+ channels | Ca channels | blood | antiarrhythmic | angina | ABCB1 | (±)-Verapamil |
| Inhibitors Related | Tebuconazole | L-Ascorbic acid | Apigenin | Fenofibrate | L-Phenylalanine | D-Menthol | Ethyl cinnamate | Naringin | L-Ascorbic acid sodium salt | Naringenin | 1-Octanol | 2-Nitrobenzoic acid |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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