Vitamin D3 NEW
| Price | $33 |
| Package | 1g |
| Supply Ability: | 10g |
| Update Time: | 2026-07-17 |
Product Details
| Product Name: Vitamin D3 | CAS No.: 67-97-0 |
| Purity: 99.93% | Supply Ability: 10g |
| Release date: 2026/07/17 |
Product Introduction
Bioactivity
| Name | Vitamin D3 |
| Description | Vitamin D3 (cholecalciferol) is a naturally occurring form of vitamin D; once metabolically activated, it can induce cellular differentiation and cancer cell proliferation. Vitamin D3 can be used to establish kidney stone models and is also an important research target in the fields of immunology and oncology. |
| In vitro | Methods: IK, RL95/2, and HEC1-A cells were treated with 2–10 μM vitamin D3 for 24, 48, or 72 hours, and cell viability was assessed using the MTT assay. Results: Vitamin D3 inhibited cell viability in a dose- and time-dependent manner, with the strongest inhibitory effect observed after 72 hours of treatment with 10 μM vitamin D3.[1] Methods: IK cells were treated with 10 μM vitamin D3 for 0–48 h. Intracellular 25(OH)D levels were measured using chemiluminescence, and VDR nuclear translocation was assessed by immunofluorescence and Western blot. Results: Vitamin D3 treatment for 48 h was required to detect 25(OH)D production, accompanied by VDR nuclear translocation.[1] |
| In vivo | Methods: Male ddY mice were divided into 4 groups (solvent control, Vitamin D3 alone, CCl? alone, Vitamin D3 + CCl?). Mice were pretreated with Vitamin D3 (5 mg/kg) administered via gavage for 4 consecutive days, followed by intraperitoneal injection of CCl? (2 g/kg) on Day 0. A separate group received a direct injection of CaCl? (150 mg/kg) to validate the role of calcium. Results: Vitamin D3 alone significantly increased serum calcium levels to 13.0 mg/dL (normal: 7.77 mg/dL), with no evidence of liver or kidney damage or oxidative stress.[2] |
| Storage | Keep away from direct sunlight,Store under nitrogen,The compound is unstable in solution. Please use soon, Pure form: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 252.5 mg/mL (656.46 mM), Sonication is recommended. (The compound is unstable in solution, please use soon.) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.6 mM), Sonication is recommended. |
| Keywords | Vitamin D-3 | Vitamin D3 | Vitamin D receptor | Vitamin D 3 | Vitamin D | VD/VDR | Type I Diabete | metastatic | Inhibitor | inhibit | Hypertension | fatal | EndogenousMetabolite | Endogenous Metabolite | Cardiovascular Disease | Cancer | calcium | absorb |
| Inhibitors Related | Sucrose | Neomycin sulfate | Aceglutamide | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Glycerol | Thymidine | Dimethyl sulfoxide | Gluconate Calcium | Sodium bicarbonate | DL-Lysine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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