VRT-532 NEW
| Price | $67 | $167 | $251 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: VRT-532 | CAS No.: 38214-71-0 |
| Purity: 99.93% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | VRT-532 |
| Description | VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Modification of CFTR by this small molecule modulator can increase arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag), thus reducing the accumulation of 4-chondroitin sulfate in cystic fibrosis. |
| In vitro | VRT-532 binds directly to G551D-CFTR in isolated systems, thereby improving its channel function and increasing its ATPase rate. VRT-325 decreased the apparent ATP affinity of purified and reconstituted F508del-CFTR[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (4 mM), Sonication is recommended. DMSO : 2.51 mg/mL (10.03 mM), Sonication is recommended. |
| Keywords | VRT-532 | VRT532 | VRT 532 | G551D-CFTR | F508del-CFTR | CFTR | CFpot-532) |
| Inhibitors Related | Glibenclamide | CFTR corrector 8 | Lumacaftor | GLPG1837 | Glucosamine | CFTR corrector 4 | IOWH-032 | Corrector C4 | Ataluren | DNDS | Glafenine | BPO-27 racemate |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Multi-Target Compound Library | Anti-Fibrosis Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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