VU 0469650 NEW
| Price | $37 | $76 | $116 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: VU 0469650 | CAS No.: 1443748-47-7 |
| Purity: 98.03% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | VU 0469650 |
| Description | VU 0469650 is a potent and selective negative allosteric modulator of mGluR1 (IC50 = 99 nM). |
| In vivo | VU 0469650 (10 mg/kg; I.P.; once; male Sprague-Dawley rats) shows an excellent selectivity profile and good exposure in both plasma and brain samples.[1] VU 0469650 (0.2 mg/kg; I.V.; once; male Sprague-Dawley rats) exhibits moderate to high clearance, a moderate volume of distribution, and a half-life of approximately 1 hour.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 45 mg/mL (123.46 mM), Sonication is recommended. DMSO : 90 mg/mL (246.93 mM), Sonication is recommended. |
| Keywords | mGluR1 |
| Inhibitors Related | IDRA-21 | Urethane | Decanoic Acid | Kynurenic acid | DCB | L-Cysteic acid monohydrate | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Memantine hydrochloride | O-Phospho-L-serine |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Glutamine Metabolism Compound Library | Neurotransmitter Receptor Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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