WS3 NEW
| Price | $35 | $64 | $123 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: WS3 | CAS No.: 1421227-52-2 |
| Purity: 99.94% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | WS3 |
| Description | WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway. |
| Cell Research | R7T1 cells are growth-arrested by removal of doxycycline for 2 days and plated into 384-well plates at a density of 3,000 cells/well in growth medium. Β cell proliferation is assessed using CellTiter Glo after 4 days. Fold increase in cell number is calculated by normalizing compound-treated wells to the median of DMSO-treated wells. (Only for Reference) |
| In vivo | In the mouse β-cell line R7T1, WS3 induces cell proliferation with an EC50 of 0.074 μM. Additionally, WS3 reversibly induces cell proliferation in primary embryonic and adult retinal pigment epithelial cells. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : < 10 mg/mL (17.56 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 250 mg/mL (438.92 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (17.56 mM), Solution. Ethanol : 74 mg/mL (129.92 mM), Sonication is recommended. |
| Keywords | β cell | WS-3 | WS3 | WS 3 | RPE | retinal | R7T1 | proliferation | pigment | pancreatic | IκB kinase | IκB | insulin | Inhibitor | inhibit | IKK | IkB/IKK | IkB | ErbB3-Binding Protein-1 (EBP1) | epithelial | diabete |
| Inhibitors Related | Amlexanox | Osimertinib | Lapatinib | Resveratrol | Erlotinib hydrochloride | Erlotinib | Neratinib | Afatinib | Chalcone | Brigatinib | Genistein | Gefitinib |
| Related Compound Libraries | Reprogramming Compound Library | NF-κB Signaling Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Stem Cell Differentiation Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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