YK-3-237 NEW
| Price | $33 | $53 | $113 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: YK-3-237 | CAS No.: 1215281-19-8 |
| Purity: 99.47% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | YK-3-237 |
| Description | YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells carrying mtp53. |
| In vitro | YK-3-237 activates SIRT1 enzyme activities in vitro and deacetylation of both mtp53 in a SIRT1-dependent manner. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.37 mM), Sonication is recommended. DMF : 30 mg/mL (80.61 mM), Sonication is recommended. Ethanol : 10 mg/mL (26.87 mM), Sonication is recommended. DMSO : 30 mg/mL (80.61 mM), Sonication is recommended. |
| Keywords | YK-3-237 | YK3237 | YK 3 237 | triple-negative | TNBC | Sirtuin | SIRT1 | p53 | Mutant | mtp53 | Inhibitor | inhibit | deacetylation | cancer | breast |
| Inhibitors Related | JGB1741 | Nicotinamide riboside malate | Sirtinol | Selisistat | MDL-800 | Dihydrocoumarin | SRT 2104 | Nicotinamide riboside | MC3482 | Fisetin | SIRT5 inhibitor 8 | Nicotinamide |
| Related Compound Libraries | Histone Modification Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Glutamine Metabolism Compound Library | Anti-Breast Cancer Compound Library | Antioxidant Compound Library | Mitochondria-Targeted Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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