Zatebradine NEW
| Price | $88 |
| Package | 2mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Zatebradine | CAS No.: 85175-67-3 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Zatebradine |
| Description | Zatebradine is a potent hyperpolarization-activated cyclic nucleotide-gated (HCN) channels inhibitor(IC50 of 1.96 μM). |
| In vitro | Zatebradine exhibits a use-dependent blockade of the cardiac pacemaker current in rabbit sino-atrial node cells (Kd 480 nM) [2]. |
| In vivo | In male C57/Bl6-mice, Zatebradine (0-20 mg/kg; intraperitoneal injection; for 30 minutes) reduces the heart rate dose-dependently from 600 to 200 bpm with ED50 value of 1.8 mg/kg and induces increasing arrhythmia[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (109.51 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 2.5 mg/mL (5.48 mM), Sonication is recommended. |
| Keywords | Zatebradine | UL-FS-49CL | UL-FS-49 | HCN channels | DopamineReceptor | Dopamine Receptor |
| Inhibitors Related | Trifluoperazine dihydrochloride | Clozapine N-Oxide | Mirtazapine | Hexamethonium Bromide | Butyrophenone | Octopamine hydrochloride | L-DOPA | Creatine | Dopamine hydrochloride | Oxolinic acid | Mianserin hydrochloride | Doxepin hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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