ZK824190 NEW
| Price | $163 | $341 | $490 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: ZK824190 | CAS No.: 2254001-81-3 |
| Purity: 98.84% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | ZK824190 |
| Description | ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA), with IC50 values of 237 nM for uPA, 1600 nM for tPA, and 1850 nM for Plasmin. |
| In vivo | In rats with experimental autoimmune encephalomyelitis (EAE) model, ZK824190 (2?mg/kg; p.o.) exhibited a relatively high oral availability(F?=?55%; Cmax=?0.64?g/mL and AUC?=?2.2?h*g/mL) and a moderate half time of 2.8 h[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.83 mM), Sonication is recommended. DMSO : 12 mg/mL (28.96 mM), Sonication is recommended. |
| Keywords | ZK-824190 | ZK824190 | ZK 824190 | Urokinase | uPA | tPA | Threonine proteases | SerineProtease | Serine proteases | Serine Protease | Serine endopeptidases | Serine | Ser/Thr Protease | protease | Plasminogen activator inhibitor-1 | plasminogen | Plasmin | PAI-1 | multiple sclerosis | Inhibitor | inhibit |
| Inhibitors Related | PMSF | AEBSF hydrochloride | Imidazole | Subtilisin | p-Aminobenzamidine dihydrochloride | Chymotrypsin | Proteinase K | Ac-Ala-OH | Trypsin | FOY 251 | 6-Aminocaproic acid | Benzamidine hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Protease Inhibitor Library | Multi-Target Compound Library | Inhibitor Library | Orally Active Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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|---|---|---|---|---|
| $1780.00 |
VIP2Y
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TargetMol Chemicals Inc.
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2026-07-15 | |
| $163.00 |
VIP6Y
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TargetMol Chemicals Inc.
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2026-07-14 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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