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2-Phenylacetamide

Catalog No.
C6905
An endogenous metabolite involved in metabolic pathways and neurotransmitter regulation.
Grouped product items
SizePriceStock Qty
5g
$50.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

2-Phenylacetamide (CAS No.: 103-81-1) is an endogenous phenylacetamide metabolite detected in mammalian systems and also isolated from plant sources such as Lepidium apetalum seeds, positioning it at the intersection of metabolic biology and natural product research. This small molecule has attracted attention in neurobiology and metabolic studies due to its involvement in diverse metabolic pathways and its potential to modulate neurotransmitter balance and intracellular signaling networks. Mechanistically, it has been reported to influence the p38 MAPK signaling pathway, which is associated with inflammatory responses, oxidative stress regulation, and fibrotic processes, thereby contributing to observed anti-inflammatory, antioxidant, anti-hypertensive, and anti-fibrotic activities in preclinical models. Although detailed quantitative potency data are limited, its biological effects are generally characterized in the micromolar concentration range in vitro, with functional outcomes dependent on cellular context and assay design. In experimental settings, 2-Phenylacetamide is widely employed as a probe to investigate metabolic network regulation, biomarker discovery, and neurotransmission-related pathways in both cell-based assays and animal models, supporting research into the pathophysiology of metabolic and neurodegenerative disorders as well as the identification of novel therapeutic targets.

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt135.16
Cas No.103-81-1
FormulaC8H9NO
SynonymsNSC 1877; α-Toluamide
Solubility≥25.5 mg/mL in DMSO; ≥12.3 mg/mL in EtOH; ≥1.26 mg/mL in H2O with ultrasonic
Chemical Name2-phenylacetamide
Canonical SMILESO=C(CC1=CC=CC=C1)N
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

2-Phenylacetamide
 

User Guide

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