一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Toggle Nav
Close
  • Menu
  • Setting

Oligomycin C

Catalog No.
C3410
mitochondrial F1FO-ATP synthase inhibitor
Grouped product items
SizePriceStock Qty
1mg
$545.00
Ship with 5-10 days
5mg
$1,635.00
Ship with 5-10 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Oligomycins are the macrolide antibiotics produced by Streptomyces species such as Streptomyces diastatochromogenes, S. libani and S. avermitilis. Oligomycins exihibited a strong toxicity against other organisms, such as Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici. Oligomycins showed no activity towards bacteria. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism.

Oligomycin C is a minor antifungal compound isolated from Streptomyces strain in soil sample that acts as an inhibitor of the mitochondrial F1FO-ATP synthase [1]. Inhibition of the ATP synthase by oligomycins resulted in cell death [2].

References:
[1].? Yang P W, Li M G, Zhao J Y, et al. Oligomycins A and C, major secondary metabolites isolated from the newly isolated strain Streptomyces diastaticus[J]. Folia microbiologica, 2010, 55(1): 10-16.
[2].? Marton A, Mihalik R, Bratincsák A, et al. Apoptotic cell death induced by inhibitors of energy conservation[J]. European journal of biochemistry, 1997, 250(2): 467-475.

Chemical Properties

Physical AppearanceA white lyophilisate
StorageStore at -20°C
M.Wt775.1
Cas No.11052-72-5
FormulaC45H74O10
Synonyms12-deoxy Oligomycin A
SolubilitySoluble in DMSO
Chemical Name(1R,?2'R,?4E,?5'S,?6S,?6'S,?7R,?8S,?10R,?11S,?12S,?14S,?15S,?16R,?18E,?20E,?22R,?25S,?28S,?29R)?-22-?ethyl-?3',?4',?5',?6'-?tetrahydro-?7,?11,?15-?trihydroxy-?6'-?[(2R)?-?2-?hydroxypropyl]?-?5',?6,?8,?10,?12,?14,?16,?28,?29-?nonamethyl-spiro[2,?26-?dioxab
Canonical SMILESO=C([C@@H](C)[C@H](O)[C@@H](C)/C=C/1)[C@H](C)[C@@H](O)[C@H](C)C([C@@H](C)[C@@H](O)[C@H](C)C/C=C/C=C/[C@@](CC)([H])CC[C@@]2([H])[C@@H](C)[C@@]([C@H](C)[C@@]3(CC[C@H](C)[C@@](C[C@H](O)C)([H])O3)O2)([H])OC1=O)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Oligomycin C
 

User Guide

英德市| 双桥区| 双流县| 富锦市| 尼玛县| 阜康市| 蒙山县| 蓬莱市| 油尖旺区| 阜城县| 元氏县| 乐业县| 晋宁县| 富阳市| 蒲城县| 肥西县| 射洪县| 廊坊市| 当阳市| 于田县| 高淳县| 灌南县| 澜沧| 宁晋县| 远安县| 青冈县| 龙泉市| 思茅市| 甘肃省| 城步| 子洲县| 余江县| 长子县| 饶阳县| 周口市| 土默特右旗| 石河子市| 白银市| 富蕴县| 拜泉县| 大新县|