一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Toggle Nav
Close
  • Menu
  • Setting

Valaciclovir

Catalog No.
A3903
Prodrug of aciclovir for herpes virus treatment
Grouped product items
SizePriceStock Qty
10mg
Please inquire
Please inquire
50mg
Please inquire
Please inquire
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

IC50 Value: 2.9 microg/ml (for HSV-1 W)[4]. Valacyclovir, the metabolic precursor of , is now approved for treatment and prevention of genital infection with herpes simplex viruses [1]. in vitro: VACV uptake was concentration dependent and saturable with a Michaelis-Menten constant and maximum velocity of 1.64 +/- 0.06 mM and 23.34 +/- 0.36 nmol/mg protein/5 min, respectively. A very similar Km value was obtained in hPEPT1/CHO cells and in rat and rabbit tissues and Caco-2 cells, suggesting that hPEPT1 dominates the intestinal transport properties of VACV in vitro [5]. in vivo: For treatment of a first episode of genital herpes, a large comparative trial has shown that valacyclovir (1 g twice a day) is as effective as acyclovir (200 mg five times a day) when given for 10 days. For treating recurrences, two trials show that valacyclovir is as effective as acyclovir (200 mg five times a day) with a treatment period of 5 days. A daily dose of 1 g of valacyclovir is as effective as 2 g daily. Valacyclovir can be administered once a day[1]. The concentrations of acyclovir in serum and CSF were measured at steady state after 6 days of oral treatment with 1,000 mg of valacyclovir three times a day [2]. EC50 values of PE and AC in 3T3 cells were 0.02 and 0.01 ug/ml, while values in BHK cells were 0.2 and 0.03 ug/ml. Treatment of infected immunosuppressed mice and FA and VA (b.i.d., 5.5 days) reduced the proportion with erythema from 100% to 24% and 38%, and eliminated ear paralysis, ear lesions (vesicles, etc) and death. Virus was absent from ear and brainstem by day 6, but reappeared after discontinuation in mice treated with VA [3]. Clinical trial: Evaluation of Valaciclovir in Patients with Chickenpox. Phage3

Chemical Properties

StorageStore at -20°C
M.Wt324.34
Cas No.124832-26-4
FormulaC13H20N6O4
SynonymsValacyclovir;Valcivir
SolubilitySoluble in DMSO
Chemical Name2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)ethyl 2-amino-3-methylbutanoate
Canonical SMILESCC(C)C(C(OCCOC[n]1c(NC(N)=NC2=O)c2nc1)=O)N
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Valaciclovir
 

User Guide

莱州市| 波密县| 交口县| 东乡| 宜章县| 托克托县| 贵阳市| 芷江| 石楼县| 桦川县| 遂昌县| 新安县| 荣昌县| 麻栗坡县| 大兴区| 贡山| 云南省| 江华| 清涧县| 衡阳县| 来宾市| 长沙市| 瑞安市| 临漳县| 丰顺县| 铁力市| 天柱县| 崇明县| 卓尼县| 武义县| 酒泉市| 那曲县| 黔南| 新泰市| 阜城县| 尼木县| 金湖县| 都匀市| 牡丹江市| 临沧市| 杭州市|