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Sulfabenzamide

Catalog No.
C6949
An antibacterial agent for localized vaginal antibacterial use, effective against Gram-positive and Gram-negative bacteria.
Grouped product items
SizePriceStock Qty
Evaluation Sample
$30.00
In stock
1g
$50.00
Ship with 5-10 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Sulfabenzamide (CAS No.: 127-71-9) is a synthetic sulfonamide-class antimicrobial compound widely utilized as a research reagent for investigating bacterial growth inhibition and sulfonamide-mediated metabolic interference. As a member of the sulfanilamide derivatives, it exerts its activity primarily through competitive inhibition of dihydropteroate synthase, thereby disrupting folate biosynthesis pathways essential for nucleic acid production in both Gram-positive and Gram-negative bacterial systems. This mechanism makes it a valuable tool for studying antimicrobial resistance, folate-dependent metabolic processes, and structure–activity relationships within sulfonamide analogs. Sulfabenzamide is frequently evaluated in combination with related agents such as sulfathiazole and sulfacetamide to explore synergistic or additive effects on microbial inhibition, reflecting its historical relevance in multi-component antibacterial formulations. In vitro studies typically demonstrate activity in the low micromolar to higher concentration ranges depending on the bacterial strain and assay conditions, supporting its use in screening platforms for antibacterial efficacy and resistance profiling. In research settings, it is applied in microbial culture assays, enzymatic inhibition studies, and comparative pharmacology models, where experimental concentrations and exposure conditions are adjusted according to specific study objectives and system requirements.

Chemical Properties

Physical AppearanceSolid
Storage -20°C
M.Wt276.31
Cas No.127-71-9
FormulaC13H12N2O3S
SynonymsN-Sulfanilylbenzamide
Solubility≥53.3 mg/mL in DMSO; ≥8.98 mg/mL in EtOH with ultrasonic; insoluble in H2O
Chemical NameN-((4-aminophenyl)sulfonyl)benzamide
Canonical SMILESO=C(C1=CC=CC=C1)NS(=O)(C2=CC=C(N)C=C2)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

Sulfabenzamide
 

User Guide

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