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Spermine NONOate

Catalog No.
B6612
nitric oxide donor
Grouped product items
SizePriceStock Qty
25mg
$137.00
Ship with 5-10 days
50mg
$259.00
Ship with 5-10 days
100mg
$459.00
Ship with 5-10 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Spermine NONOate (CAS: 136587-13-8) is a diazeniumdiolate-type nitric oxide (NO) donor. It releases NO, stimulating guanylate cyclase activity and subsequently elevating intracellular cyclic GMP (cGMP) levels. In rat pulmonary artery studies, application of Spermine NONOate (100 μM) enhanced cGMP levels by approximately 35-fold, driving relaxation events via activation of ion pumps and channels including sarco/endoplasmic reticulum Ca2?-ATPase, Na?/K?-ATPase, and Ca2?-activated K? channels. Additionally, this molecule attenuates copper sulfate-induced oxidation of human LDL and reduces surgical adhesion formation in animal models.

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at -80°C
M.Wt262.35
Cas No.136587-13-8
FormulaC10H26N6O2
SolubilitySoluble in H2O
Chemical NameN'-(3-aminopropyl)-N'-(4-((3-aminopropyl)amino)butyl)-N-hydroxynitrous hydrazide
Canonical SMILESNCCCNCCCCN(CCCN)N(N=O)O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Spermine NONOate
 

User Guide

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