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ω-Agatoxin IVA

Catalog No.
B7192
P-type calcium channels blocker
Grouped product items
SizePriceStock Qty
10ug
$322.00
Ship with 5-10 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

ω-Agatoxin IVA (CAS 145017-83-0) is a peptide neurotoxin isolated originally from spider venom. It selectively inhibits voltage-gated P/Q-type calcium channels (Cav2.1), blocking calcium ion influx across neuronal membranes. By binding with high affinity to these calcium channels, ω-Agatoxin IVA suppresses neurotransmitter release at presynaptic terminals. Researchers routinely utilize ω-Agatoxin IVA to investigate neurotransmission, presynaptic calcium signaling, and the physiological or pathological roles of P/Q-type calcium channels in neuronal function.

Product Citation

Chemical Properties

Physical AppearanceWhite lyophilised solid
StorageDesiccate at -20°C
M.Wt5202.25
Cas No.145017-83-0
FormulaC217H360N68O60S10
SolubilitySoluble in H2O
Canonical SMILESCCC(C1/C(O)=N/C(/C(O)=N/C(/C(O)=N\C(/C(O)=N/C(/C(O)=N/C/C(O)=N/C(/C(O)=N/C(C(O)=NC(C(O)=NC(C(O)=NCC(O)=NCC(O)=NC(C2=O)C(O)C)CC3=CNC4=CC=CC=C34)CCCCN)CSSCC5/C(O)=N/C(/C(O)=N/C(/C(O)=N/C(/C(O)=N/C(/C(O)=N\C(/C(O)=N/C/C(O)=N/C(/C(O)=N/C(/C(O)=N/6)CC(O)=N)C(O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

User Guide

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