Lofepramine
Catalog No.
B7097
Serotonin and noradrenalin re-uptake inhibitor (SNRI)
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Lofepramine is a tricyclic small-molecule compound. As an antidepressant, it increases the transmission efficiency of these neurotransmitters by inhibiting the reuptake of norepinephrine and 5-hydroxytryptamine. Studies show that its metabolite, Desipramine, remains active and affects the central nervous system. This compound is widely used in clinical research and therapeutic exploration for depression and anxiety-related disorders.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 418.97 |
| Cas No. | 23047-25-8 |
| Formula | C26H27N2OCl |
| Solubility | ≥16.37 mg/mL in DMSO with ultrasonic; ≥5.24 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | 1-(4-chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethanone |
| Canonical SMILES | CN(CCCN(c1c(CC2)cccc1)c1c2cccc1)CC(c(cc1)ccc1Cl)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
