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1-?????-1-???????????

1-?????-1-???????????
1-?????-1-??????????? ??? ???
?? ??:
931-97-5
???:
1-?????-1-???????????
???(??):
1-?????-1-???????????
???:
1-HYDROXY-1-CYCLOHEXANECARBONITRILE
???(??):
1-HYDROXY-CYCLOHEXANECARBONITRILE;213-246-0;CYCLOHEXANONE CYANOHYDRIN;1-Hydroxy-1-cyanocyclohexane;1-Cyano-1-hydroxycyclohexane;Cyclohexanone cyanohydrin 98%;Cyclohexanone cyanohydrin, 98%,;1-Hydroxy-cyclohexancarbonitril;1-hydroxy-cyclohexanecarbonitril;1-Hydroxy-1-cyclohexancarbonitril
CBNumber:
CB5255487
???:
C7H11NO
??? ??:
125.17
MOL ??:
931-97-5.mol

1-?????-1-??????????? ??

???
32-35 °C (lit.)
?? ?
132 °C/19 mmHg (lit.)
??
1.031
???
1.4693
???
>230 °F
?? ??
2-8°C
?? ?? (pKa)
11.45±0.20(Predicted)
InChI
1S/C7H11NO/c8-6-7(9)4-2-1-3-5-7/h9H,1-5H2
InChIKey
ZDBRPNZOTCHLSP-UHFFFAOYSA-N
SMILES
OC1(CCCCC1)C#N
CAS ??????
931-97-5(CAS DataBase Reference)
EPA
Cyclohexanone cyanohydrin (931-97-5)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T+
?? ???? ?? 28
????? 45
????(UN No.) UN 2811 6.1/PG 2
WGK ?? 3
RTECS ?? GU7710000
TSCA TSCA listed
?? ?? 6.1
???? II
???? ??? 6.1B - Non-combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Oral
????(GHS): Skull and Crossbones (GHS06)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H300 ??? ???? ?? ?? ?? - ?? ?? 1,2 ?? P264, P270, P301+P310, P321, P330,P405, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P301+P310 ???? ?? ????(??)? ??? ????.
NFPA 704
1
4 0

1-?????-1-??????????? C??? ??, ??, ??

??

Cyclohexanone cyanohydrin was employed as substrate during high-throughput screening assay for hydroxynitrile lyase activity. It was used in preparation of 1-aminomethyl cyclohexanol via catalytic hydrogenation reaction.

?? ??

Brown solid.

??? ?? ??

Water soluble. Reacts slowly with water .

?? ???

1-HYDROXY-1-CYCLOHEXANECARBONITRILE is an a-hydroxonitrile. Incompatible with acids; mixing nitriles with strong oxidizing acids can lead to violent reactions. Incompatible with oxidizing agents such as peroxides and epoxides. Mixing with bases can produce poisonous and flammable hydrogen cyanide. May be hydrolyzed exothermically in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). May react vigorously with reducing agents.

????

Flash point data regarding 1-HYDROXY-1-CYCLOHEXANECARBONITRILE are not available, however, 1-HYDROXY-1-CYCLOHEXANECARBONITRILE is probably combustible.

1-?????-1-??????????? ?? ?? ? ???

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