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[CAS NO. 118-08-1]??Hydrastine

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PRODUCTS SPECIFICATIONS [118-08-1]

Catalog
HY-B0927
Brand
MCE
CAS
118-08-1

DESCRIPTION [118-08-1]

Overview

MDL-
Molecular Weight383.39
Molecular FormulaC21H21NO6
SMILESO=C1O[C@H]([C@@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=C1C(OC)=C(OC)C=C5

For research use only. We do not sell to patients.

Summary

Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 260.83 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6083 mL 13.0415 mL 26.0831 mL
5 mM 0.5217 mL 2.6083 mL 5.2166 mL
10 mM 0.2608 mL 1.3042 mL 2.6083 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (6.52 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.52 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.52 mM); Clear solution

* All of the co-solvents are available by MCE.

Synonyms

1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)-
Hydrastine
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-
1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv.
(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
β-Hydrastine
(-)-β-Hydrastine
l-Hydrastine
(-)-Hydrastine
(1R,9S)-β-Hydrastine

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