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[CAS NO. 123-31-9]??Hydroquinone

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PRODUCTS SPECIFICATIONS [123-31-9]

Catalog
SLK-S4580
Brand
Selleck
CAS
123-31-9

DESCRIPTION [123-31-9]

Overview

MDL-
Molecular Weight110.11
Molecular FormulaC6H6O2
SMILESOC1=CC=C(O)C=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM9.0818 mL45.4091 mL90.8183 mL
5 mM1.8164 mL9.0818 mL18.1637 mL
10 mM0.9082 mL4.5409 mL9.0818 mL
50 mM0.1816 mL0.9082 mL1.8164 mL

Description

Hydroquinone (Quinol, 1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ) is a Inhibitor. The physiologic effect of hydroquinone is by means of Depigmenting Activity. It also posesses antioxidant properties that can cause toxicity in several organs, notably the kidney.

In vitro

At 50 μM HQ(Hydroquinone), R-28 cells show a significant decrease in cell viability compared with the dimethyl sulfoxide (DMSO)-treated controls. At the 100–500 μM concentrations, all three cell lines show significant cell death (P <0.001). In the ARPE-19, R-28, and HMVEC cultures, the caspase-3/7 activities are not increased at any of the HQ concentration. Neuroretinal R-28 cells are more sensitive to HQ than the ARPE-19 and HMVEC cultures.

In vivo

In vivo exposure of rats to HQ results in changes of immune response mirrored by impairing allergic lung response to ovalbumin, an antigen unrelated to HQ. HQ exposure impairs the expression of CD45R and CD6 co-stimulatory molecules on activated spleen lymphocytes and diminishes the levels of OA(ovalbumin)-anaphylactic antibodies and the subsequent mast cell degranulation in sensitized rats challenged with OA.


Synonyms

1,4-Benzenediol
Hydroquinone
Arctuvin
p-Benzenediol
Benzohydroquinone
Benzoquinol
p-Dihydroxybenzene
Eldoquin
Hydroquinol
Quinol
Tecquinol
Tenox HQ
p-Dioxybenzene
p-Hydroquinone
1,4-Dihydroxybenzene
p-Hydroxyphenol
HE 5
Diak 5
Eldopaque
Phiaquin
4-Hydroxyphenol
Dihydroquinone
p-Quinol
BQ(H)
p-Dihydroquinone
1,4-Benzoquinol
p-Phenylenediol
Eldoquin Forte
Solaquin Forte
Black & White Bleaching Cream
Eldopacque
Aida
Eldopaque Forte
NSC 9247
Solution Q
1,4-p-Benzenediol
1,4-Phenylenediol
1,4-Benzenediol (hydroquinone)

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