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[CAS NO. 1264-62-6]??Erythromycin Ethylsuccinate

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PRODUCTS SPECIFICATIONS [1264-62-6]

Catalog
HY-B0957
Brand
MCE
CAS
1264-62-6

DESCRIPTION [1264-62-6]

Overview

MDLMFCD00084692
Molecular Weight862.05
Molecular FormulaC43H75NO16
SMILESO=C(CCC(OCC)=O)O[C@H]([C@H]1N(C)C)[C@](O[C@H](C)C1)([H])O[C@@H]([C@](O)(C[C@H](C([C@@H]([C@@H](O)[C@@]2(O)C)C)=O)C)C)[C@H]([C@@H]([C@H](C(O[C@@H]2CC)=O)C)O[C@@](O[C@@H](C)[C@@H]3O)([H])C[C@@]3(C)OC)C

For research use only. We do not sell to patients.

Summary

Erythromycin Ethylsuccinate is an antibiotic useful for the treatment of a number of bacterial infections, has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin Ethylsuccinate has antiviral activity against HIV-1 .


IC50 & Target

HIV-1


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT01972022 A.O. Ospedale Papa Giovanni XXIII
Coronary Artery Lesions
November 2013 Phase 4
NCT04894734 Nandan Lad, M.D., Ph.D.|Duke University
Spinal Cord Injury at T1-T12 Level|Traumatic Thoracic Spinal Cord Contusion|Thoracic Spinal Cord Trauma|Traumatic Thoracic Spinal Cord Laceration|Post-Traumatic Thoracic Myelopathy|Traumatic Thoracic Spinal Cord Myelopathy
August 1, 2022 Not Applicable
NCT01266239 Shin Yukuhashi Hospital|Abbott Medical Devices|Cordis Corporation
Ischemic Heart Disease
July 2010 Not Applicable

Appearance

Solid


Source

Saccharopolyspora erythraea


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL ( 58.00 mM )

Ethanol : ≥ 33.33 mg/mL ( 38.66 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1600 mL 5.8001 mL 11.6003 mL
5 mM 0.2320 mL 1.1600 mL 2.3201 mL
10 mM 0.1160 mL 0.5800 mL 1.1600 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (2.90 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.90 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Erythromycin, 2′-(ethyl butanedioate)
Erythromycin, mono(ethyl succinate) (ester)
Erythromycin ethyl succinate
Erythromycin, 2′-(ethyl succinate)
Succinic acid, ethyl ester, monoester with erythromycin
Oxacyclotetradecane, erythromycin deriv.
Erythrocin ethyl succinate
Pediamycin
Erythroped
Evesin
Eritrocina
Esinol
EryPed
Paediathrocin
Erythro ES
Wyamycin E
Sigapedil
Durapaediat
Eryliquid
EES
Arpimycin
Erythro-Holz
Refkas
Anamycin
E-Mycin e
Monomycin

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