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[CAS NO. 134332-50-6]??Galanthamine N-Oxide

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PRODUCTS SPECIFICATIONS [134332-50-6]

Catalog
HY-N7263
Brand
MCE
CAS
134332-50-6

DESCRIPTION [134332-50-6]

Overview

MDL-
Molecular Weight303.35
Molecular FormulaC17H21NO4
SMILESO[C@H]1C=C[C@@]23CC[N@@+](C)([O-])CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24

For research use only. We do not sell to patients.

Summary

Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor . Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC 50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes [1] [2] .


IC50 & Target

AChE

BChE


Appearance

Crystal



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)


Solvent & Solubility

In Vitro:

DMSO : 6.25 mg/mL ( 20.60 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2965 mL 16.4826 mL 32.9652 mL
5 mM 0.6593 mL 3.2965 mL 6.5930 mL
10 mM 0.3297 mL 1.6483 mL 3.2965 mL
* Please refer to the solubility information to select the appropriate solvent.


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