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[CAS NO. 13849-08-6]??S-(+)-Marmesin

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PRODUCTS SPECIFICATIONS [13849-08-6]

Catalog
HY-N2176
Brand
MCE
CAS
13849-08-6

DESCRIPTION [13849-08-6]

Overview

MDL-
Molecular Weight246.26
Molecular FormulaC14H14O4
SMILESO=C1C=CC2=CC3=C(O[C@H](C(C)(O)C)C3)C=C2O1

For research use only. We do not sell to patients.

Summary

S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.


IC50 & Target

COX-2

5-LOX


In Vitro

S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a K m of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism [1] . S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity [2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 2 mg/mL ( 8.12 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0607 mL 20.3037 mL 40.6075 mL
5 mM 0.8121 mL 4.0607 mL 8.1215 mL
10 mM --- --- ---
* Please refer to the solubility information to select the appropriate solvent.


Synonyms

7H-Furo[3,2-g][1]benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (2S)-
Marmesin
7H-Furo[3,2-g][1]benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-
7H-Furo[3,2-g][1]benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-(+)-
(2S)-2,3-Dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one
(+)-Marmesin
S-(+)-Marmesin
(S)-Marmesin
NSC 340840

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