[CAS NO. 14028-44-5]??Amoxapine

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PRODUCTS SPECIFICATIONS [14028-44-5]

Catalog

HY-B0991

Brand

MCE

CAS

14028-44-5

DESCRIPTION [14028-44-5]

Overview

MDL	MFCD00069210
Molecular Weight	313.78
Molecular Formula	C17H16ClN3O
SMILES	ClC1=CC=C(OC2=CC=CC=C2N=C3N4CCNCC4)C3=C1

For research use only. We do not sell to patients.

2 Publications Citing Use of MCE

[1]Nat Commun. 2022 Nov 10;13(1):6796.
[2]PLoS Negl Trop Dis.?2019 Aug 20;13(8):e0007681.

Summary

Amoxapine is a tetracyclic antidepressant of the dibenzoxazepine family, though it is often classified as a secondary amine tricyclic antidepressant.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 8.33 mg/mL ( 26.55 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1869 mL	15.9347 mL	31.8695 mL
5 mM	0.6374 mL	3.1869 mL	6.3739 mL
10 mM	0.3187 mL	1.5935 mL	3.1869 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 1.56 mg/mL (4.97 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1.56 mg/mL (4.97 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1.56 mg/mL (4.97 mM); Clear solution

* All of the co-solvents are available by MCE.

Synonyms

Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(1-piperazinyl)-

2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine

Amoxapine

CL 67772

Demolox

Moxadil

Amoxan

Asendin

Asendis

2-Chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine

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