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[CAS NO. 2920-86-7]??Prednisolone hemisuccinate

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PRODUCTS SPECIFICATIONS [2920-86-7]

Catalog
HY-B1087
Brand
MCE
CAS
2920-86-7

DESCRIPTION [2920-86-7]

Overview

MDL-
Molecular Weight460.52
Molecular FormulaC25H32O8
SMILESC[C@@]12[C@](C(COC(CCC(O)=O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O

For research use only. We do not sell to patients.

Summary

Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 542.86 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1715 mL 10.8573 mL 21.7146 mL
5 mM 0.4343 mL 2.1715 mL 4.3429 mL
10 mM 0.2171 mL 1.0857 mL 2.1715 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution

* All of the co-solvents are available by MCE.

Synonyms

Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11β)-
Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-, 21-(hydrogen succinate)
(11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxypregna-1,4-diene-3,20-dione
Δ1-Hydrocortisone 21-hemisuccinate
Prednisolone hemisuccinate
Prednisolone 21-hemisuccinate
Prednisolone succinate
Prednisolone bisuccinate
Prednisolone 21-succinate
Prednisolut
Prednisolone 21-O-β-carbonylpropionic acid

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